{"id":1688,"date":"2024-11-26T15:24:49","date_gmt":"2024-11-26T14:24:49","guid":{"rendered":"https:\/\/fondation-autisme.org\/risque-toxicologique\/"},"modified":"2025-09-26T23:27:33","modified_gmt":"2025-09-26T21:27:33","slug":"toxicological-and-or-immunological-incident","status":"publish","type":"post","link":"https:\/\/fondation-autisme.org\/en\/toxicological-and-or-immunological-incident\/","title":{"rendered":"Toxicological and\/or immunological incident"},"content":{"rendered":"

Higher rates of autism diagnosis in recent years suggest involvement of environmental factors in causing this developmental disorder, notwithstanding genetic risk factors. Autistic children exhibit evidence of oxidative stress and impaired methylation, which may reflect effects of toxic exposure on sulfur metabolism. <\/p>\n

Note : the above is largely inspired by Deth R, Muratore C, Benzecry J, Power-Charnitsky VA, Waly M: How environmental and genetic factors combine to cause autism: a redox\/methylation hypothesis. Neurotoxicology. 2008, 29: 190-201. 10.1016\/j.neuro.2007.09.010.<\/i><\/p>\n<\/div><\/div><\/div>

There are probably many environmental factors and they can potentially be combined. Following a workshop entitled “Exploring the Environmental Causes of Autism and Learning Disabilities” and organised with the support of the National Institute of Environmental Health Sciences (NIEHS) and the Autism Speaks association, the Mount Sinai Children’s Environmental Health Center compiled as early as 2011 a list of 10 chemical compounds suspected of neurodevelopmental toxicity:<\/p>\n